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    Minerva-35 Tablet

    Uses, Side-effects, Reviews, and Precautions

    Medicines Southafrica Minerva-35 Tablet
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    What is Minerva-35?

    Minerva-35 Tablet is used for Severe acne in women, Prevention of pregnancy, Oral contraception, Severe acne or excessive hair growth on the face and body in women, Advanced prostate cancer, Excessive hair growth on the face and body in women, Early puberty, Male hypersexuality and other conditions. Minerva-35 Tablet may also be used for purposes not listed in this medication guide.
    Minerva-35 Tablet contains Cyproterone Acetate and Ethinylestradiol as active ingredients.
    Minerva-35 Tablet works by reducing the production of as well as blocking male sex hormone testosterone in the body; inhibiting the ovulation;
    Bayer manufactures Minerva-35 Tablet.
    Detailed information related to Minerva-35 Tablet's uses, composition, dosage, side effects and reviews is listed below.

    Minerva-35 Tablet Uses

    Minerva-35 Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
    References: 1, 2
    Learn more: Uses

    Minerva-35 Tablet - Composition and Active Ingredients

    Minerva-35 Tablet is composed of the following active ingredients (salts)
    Please note that this medicine may be available in various strengths for each active ingredient listed above.

    Minerva-35 Tablet - Side-effects

    The following is a list of possible side-effects that may occur from all constituting ingredients of Minerva-35 Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
    If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
    References: 2, 3, 4
    Learn more: Side-effects

    Minerva-35 Tablet Working, Mechanism of Action and Pharmacology

    Minerva-35 Tablet improves the patient's condition by performing the following functions:
    References: 2, 5

    Minerva-35 Tablet - Precautions & How to Use

    Before using Minerva-35 Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
    • Age above 35 years
    • Avoid smoking during drug intake
    • Consult a doctor if you have diabetes, obesity, undiagnosed vaginal bleeding, mild hypertension, migraine, mental illness or gallbladder disease
    • Continue to take calcium, vitamin D and vitamin B12 in your diet or in supplements while taking this medication
    • Fatigue
    • Have regular breast and gynecology exams while on this medication
    • If you begin to develop feminine traits and are male, consult your doctor on whether you should continue this medication
    • Monitor blood glucose as this medication may increase blood sugar levels
    • This medicaiton does not prevent the spread of sexually transmitted diseases like HIV
    • This medication may increase chance of stroke or heart attack
    References: 2, 2

    Minerva-35 Tablet - Drug Interactions

    If you use other drugs or over the counter products at the same time, the effects of Minerva-35 Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Minerva-35 Tablet may interact with the following drugs and products:
    • Alcohol
    • Aminoglutethimide
    • Antibiotics
    • Anticoagulants
    • Carbamazepine
    • Dicoumarol
    • Ethinyl estradiol
    • Hydrocortisone
    • Phenobarbital
    • Prednisolone
    References: 2
    Learn more: Interactions

    Minerva-35 Tablet - Contraindications

    Hypersensitivity to Minerva-35 Tablet is a contraindication. In addition, Minerva-35 Tablet should not be used if you have the following conditions:
    • Active liver disease
    • Alcohol
    • Avoid postoperative thromboembolism
    • Coronary and cerebrovascular diseases or a history of it
    • Diabetes mellitus
    • Galactose intolerance
    • Glucose galactose malabsorption
    • History of jaundice during past pregnancy
    • Hyperlipidaemia
    • Hypersensitivity
    References: 2
    Learn more: Contraindications

    Minerva-35 Tablet - Frequently asked Questions

    • Is Minerva-35 Tablet safe to consume or apply when pregnant?
      • Cyproterone Acetate: No
      • Ethinylestradiol: Please consult with your doctor for case-specific recommendations.
      References: 2
    • Is Minerva-35 Tablet safe while breastfeeding?
      • Cyproterone Acetate: Please discuss the risks and benefits with your doctor.
      • Ethinylestradiol: Please discuss the risks and benefits with your doctor.
      References: 2
    • Can Minerva-35 Tablet be used for severe acne in women and prevention of pregnancy?
      Yes, severe acne in women and prevention of pregnancy are among the most common reported uses for Minerva-35 Tablet. Please do not use Minerva-35 Tablet for severe acne in women and prevention of pregnancy without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Minerva-35 Tablet.
    • How long do I need to use Minerva-35 Tablet before I see improvement of my conditions? website users have reported 1 week and 3 months as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Minerva-35 Tablet. Click here and view survey results to find out what other patients report as time for effectiveness for Minerva-35 Tablet.
    • Should I consume Minerva-35 Tablet empty stomach, before food or after food? website users have most commonly reported consuming Minerva-35 Tablet after food. However, this may not be reflective of how you should consume this medicine. Please follow your doctor's advice on how you should use this medicine. Click here and view survey results to find out what other patients report as timing of using Minerva-35 Tablet.
    • Is it safe to drive or operate heavy machinery when consuming?
      If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Minerva-35 Tablet medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Minerva-35 Tablet. Always consult with your doctor for recommendations specific to your body and health conditions.
    • Is this medicine or product addictive or habit forming?
      Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
    • Can it be stopped immediately or do I have to slowly ween off consumption?
      Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

    Other important Information on Minerva-35 Tablet

    Missing a dose

    In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
    References: 6, 7, 8, 9

    Overdosage of Minerva-35 Tablet

    • Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Minerva-35 Tablet, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
    • Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
    • Please consult your physician or pharmacist or product package for more information.
    References: 10, 11, 12

    Storage of Minerva-35 Tablet

    • Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
    • Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Minerva-35 Tablet.
    References: 13, 14, 15, 16

    Expired Minerva-35 Tablet

    • Taking a single dose of expired Minerva-35 Tablet is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
    References: 17, 18

    Dosage Information

    Please consult your physician or pharmacist or refer to product package.

    Minerva-35 Tablet - Packages and Strengths

    Minerva-35 Tablet is available in the following packages and strengths
    Minerva-35 Tablet - Packages: 28

    Minerva-35 Tablet - Manufacturers

    The medicine is manufactured by the following companies


    1. Neumann F, Töpert M (November 1986). "Pharmacology of antiandrogens". Journal of Steroid Biochemistry. 25 (5B): 885–95. doi:10.1016/0022-4731(86)90320-1. PMID 2949114.
    2. DailyMed LABEL: AUBRA - levonorgestrel and ethinyl estradiol - Accessed: October 12, 2016. (Accessed on 12/17/16)
    3. Regidor PA, Spper K, Regidor M, Schindler EM. [Long-term side-effects following cyproterone acetate containing therapy in gynecology]. Zentralbl Gynakol 2000; 122(5):268-73. PMID: 10857213
    4. Moore E, Wisniewski A, Dobs A. Endocrine treatment of transsexual people: a review of treatment regimens, outcomes, and adverse effects. Journ Clin Endocrin Metab. 2003; 88(8):3467-73.
    5. Neumann F (1994). "The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research" (PDF). Exp. Clin. Endocrinol. 102 (1): 1–32. doi:10.1055/s-0029-1211261. PMID 8005205.
    6. - Accessed: July 14, 2016.
    7. - Accessed: July 3, 2016.
    8. Cancer.Net (2014). - Accessed: July 3, 2016.
    9. Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). - Accessed: May 28, 2016.
    10. National Institute of Drug Abuse (2010). - Accessed: July 21, 2016.
    11. eMedicinehealth (2016). - Accessed: July 21, 2016.
    12. Centers for Disease Control and Prevention (2010). - Accessed: July 21, 2016.
    13. Centers for Disease Control and Prevention. December 12, 2011. - Accessed: June 10, 2016.
    14. The Center for Improving Medication Management and the National Council on Patient Information and Education. - Accessed: June 10, 2016.
    15. U.S. Food and Drug Administration. December 24, 2013. - Accessed: June 10, 2016.
    16. World Health Organization: - Accessed: July 1, 2016.
    17. Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
    18. Harvard Medical School (2016). - Accessed: May 1, 2016.

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    • Minerva-35 Tablet - Uses, Side-effects, Reviews, and Precautions - Bayer - - South Africa. (n.d.). Retrieved June 23, 2018, from

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    Last updated date

    This page was last updated on 6/13/2018.
    This page provides information for Minerva-35 Tablet in English.
    Read Reviews » Minerva-35 Tablet

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