Intelligence » Amyotrophic Lateral Sclerosis » Last Week

    Subscribe to get latest posts via email or subscribe to a RSS feed.

    Friday, January 19, 2018 -- Scientists say they have described for the first time atom-by-atom changes in a protein family linked to amyotrophic lateral sclerosis (ALS). Their study (“ Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation ”) is published in Molecular Cell.  “hnRNPA2, a component of RNA-processing membraneless organelles, forms inclusions when mutated in a syndrome characterized by the degeneration of neurons (bearing features of amyotrophic lateral sclerosis [ALS] and frontotemporal dementia), muscle, and bone. Here we provide a unified structural view of hnRNPA2 self-assembly, aggregation, and interaction and the distinct effects of small chemical changes—disease mutations and arginine methylation—on these assemblies,” write the investigators. “The hnRNPA2 low-complexity (LC) domain is compact and intrinsically disordered

    Related pages

    librax ingredientsindapamidasyndolsodium polystyrene sulfonate mechanism of actionhairbless tablets mankindvalance solutionschering plough brinnyzentel tablet is used fordeflate medicinefimal and mal ovar sex tablet tabletwise.compiriton syrup usesurofitvicks inhaler ingredientsmedicine ciplar 40visine eye drops price philippinesnyquil indicationsuses of mink oilzapiz 0.5 tabletside effects of feroglobin capsulesaccu chek sensornomi tabletcytarabine side effectssomazina dosagetazac diseasewhat is fertilaidfree letixdaktacort hemorrhoidsminipress 5mgalfa teclactic acid bacillus useswhat is thymoglobulinpiperaquine phosphatefheal lupiniron 3 hydroxidefoster asthma inhalerzytiga and alcoholprozine syrup usageabsolute tabletrabalkem dsraldon sayrup hindiaroxyglenmark product list indiabetnovate c usearip 10mgfheal lupintyphoid disease in hindilonart suspension dosageomnicef medicationtalen bromazepamtorex medicineorgamed tabletinova tabletmylanta double strength liquidaceclofenac ipVaginal Cream কাজ কিzircon usesflumedbenzydamine mouthwash indiauses for lidocaine ointmentceftum 500mg tablet used forelaprase infusionvitacap capsules side effectstab dothipmetaprimtretinoin minoxidilapixaban usesbenadryl chesty fortenitrol 2 ointmentpiperazine syrupoleanz 5methylcobalamin injection dosetransamin capsule in pregnancywhat is reyataz used forsalbutamol syrup for kidscadex drugxylocaine jelly 5thyroxine tablets ingredientsEzilax in hinditablet domstaltab ln bloc 10 mgtinicide